胥波教授
胥波，東華大學(xué)化學(xué)與化工學(xué)院教授，博士生導(dǎo)師。于華東理工大學(xué)獲得學(xué)士和碩士學(xué)位，并于2008年在美國路易斯維爾大學(xué)獲得博士學(xué)位。2008-2014為美國路易斯維爾大學(xué)化學(xué)系研究助理教授。2014年末在東華大學(xué)開始工作，主要研究方向?yàn)橛袡C(jī)合成方法學(xué)及反應(yīng)機(jī)理研究、藥物化學(xué)、有機(jī)合成自動(dòng)化儀器研發(fā)等。在東華大學(xué)工作期間，胥波博士發(fā)表了超過80篇SCI論文，其中包括Angew. Chem. , JACS, Chem., Org. Lett. 等雜志上發(fā)表的關(guān)于新型氟化反應(yīng)，過渡金屬催化等較有影響力的論文，并獲得了多項(xiàng)專利。胥波博士還率先提出了Rigid SolventTM等技術(shù)，可以大大提高有機(jī)合成的速度和效率。
研究方向：
1. 有機(jī)合成方法學(xué)。
2. 有機(jī)反應(yīng)機(jī)理研究（物理有機(jī)化學(xué)）。
3. 有機(jī)合成自動(dòng)化系統(tǒng)研發(fā)。
近年來承擔(dān)的主要科研項(xiàng)目：
1. 國家自然科學(xué)基金面上項(xiàng)目，21871046，放射性氟同位素18F引入的點(diǎn)擊化學(xué)，2019-2022
2. 國家自然科學(xué)基金面上項(xiàng)目，22071022， 對(duì)有機(jī)合成反應(yīng)中的緊密離子對(duì)的系統(tǒng)研究，2021至2024
近年來發(fā)表的代表性論著、專利：
1.Chen, G.; Xu, B., Hydrogen Bond Donor and Unbalanced Ion Pair Promoter-Assisted Gold-Catalyzed Carbon–Oxygen Cross-Coupling of (Hetero)aryl Iodides with Alcohols. ACS Catal. 2023, 13, 1823-1829.
2.Yang, R.-Y.; Gao, X.; Gong, K.; Wang, J.; Zeng, X.; Wang, M.; Han, J.; Xu, B., Synthesis of ArCF2X and [18F]Ar-CF3 via Cleavage of the Trifluoromethylsulfonyl Group. Org. Lett. 2022, 24, 164-168.
3.Yang, J.; Li, G.; Yu, K.; Xu, B.; Chen, Q., Electrochemical Sulfonylation-Induced Lactonization of Alkenes: Synthesis of Sulfonyl Phthalides. J. Org. Chem. 2022, 87, 1208-1217.
4.Wang, H.; Yang, R.-Y.; Xu, B., Synthesis of Cyclopropenes and Fluorinated Cyclopropanes via Michael Initiated Ring Closure of Alkyl Triflones. Chem. - Eur. J. 2022, 28, e202104364.
5.Peng, P.; Yang, R. Y.; Xu, B., Tunable Reduction of Benzyl α , α ‐Difluorotriflones: Synthesis of Difluoroarenes and Sodium Aryldifluoromethyl Sufinates and their Applications. ChemistrySelect 2022, 7.
6.Mudshinge, S. R.; Yang, Y.; Hammond, G. B.; Lu, Z.; Xu, B., Gold (I/III)-Catalyzed Trifluoromethylthiolation and Trifluoromethylselenolation of Organohalides. Angew. Chem. Int. Ed. Engl. 2022, 61, e202115687.
7.Man, Y.; Liu, S.; Xu, B.; Zeng, X., N-Heterocyclic-Carbene-Catalyzed C–H Acylation via Radical Relay. Org. Lett. 2022, 24, 944-948.
8.Liu, S.; Zhang, Y.; Gong, K.; Zeng, X.; Xie, F.; Xu, B.; Han, J., Widely applicable (radio)dihalogenation of alkynes and alkenes using two different nucleophilic alkali metal halides. Org. Chem. Front. 2022, 9, 6826-6832.
9.Liu, S.; Tormena, C. F.; Hammond, G. B.; Xu, B., Broadly Applicable Ion Pair-Assisted Nucleophilic Substitution of sp3-Carbon Electrophiles with Alkynyltrifluoroborates. Org. Lett. 2022, 24, 6298-6303.
10.Li, T.; Xu, B., Faster and greener parallel chemical reaction work-up using ‘sponge’ extraction. Tetrahedron Lett. 2022, 95, 153702.
11.Gao, X.; Gong, K.; Han, J.; Wang, M.; Xu, B., Preparation of [(18)F]Alkenyl Fluorides Using No-Carrier-Added [(18)F]AgF via Silver-Mediated Direct Radiofluorination of Alkynes. Org. Lett. 2022, 24, 6438-6442.
12.Chen, G.; Xu, B., Divergent Synthesis of Sulfonyl Quinolines, Formyl Indoles, and Quinolones from Ethynyl Benzoxazinanones via AuI Catalysis, AuI-ArI Co-Catalysis, and Silver Catalysis. ACS Catal. 2022, 12, 7134-7141.
13.Zhao, B.; Hammond, G. B.; Xu, B., Modulation of photochemical oxidation of thioethers to sulfoxides or sulfones using an aromatic ketone as the photocatalyst. Tetrahedron Lett. 2021, 82, 153376.
14.Zhao, B.; Hammond, G. B.; Xu, B., Aromatic Ketone-Catalyzed Photochemical Synthesis of Imidazo-isoquinolinone Derivatives. J. Org. Chem. 2021, 86, 12851-12861.
15.Yang, Y.; Gao, X.; Zeng, X.; Han, J.; Xu, B., Hydrogen-Bond-Donor Solvents Enable Catalyst-Free (Radio)-Halogenation and Deuteration of Organoborons. Chem. Eur. J. 2021, 27, 1297-1300.
16.Yang, R.-Y.; Xu, B., Chemo-, regio- and stereoselective synthesis of monofluoroalkenes via a tandem fluorination–desulfonation sequence. Chem. Commun. 2021, 57, 7802-7805.
17.Yang, R.-Y.; Wang, H.; Xu, B., Base promoted gem-difluoroolefination of alkyl triflones. Chem. Commun. 2021, 57, 4831-4834.
18.Lu, Z.; Li, T.; Mudshinge, S. R.; Xu, B.; Hammond, G. B., Optimization of Catalysts and Conditions in Gold(I) Catalysis—Counterion and Additive Effects. Chem. Rev. 2021, 121, 8452-8477.
19.Liu, S.; Meng, L.; Zeng, X.; Hammond, G. B.; Xu, B., Synthesis of Acrylonitriles via Mild Base Promoted Tandem Nucleophilic Substitution-Isomerization of α-Cyanohydrin Methanesulfonates. Chin. J. Chem . 2021, 39, 913-917.
20.Liang, Q.; Lin, L.; Li, G.; Kong, X.; Xu, B., Synthesis of Phenanthridine and Quinoxaline Derivatives via Copper-Catalyzed Radical Cyanoalkylation of Cyclobutanone Oxime Esters and Vinyl Azides. Chin. J. Chem . 2021, 39, 1948-1952.
21.Li, W.; Lu, Z.; Hammond, G. B.; Xu, B., Unbalanced-Ion-Pair-Catalyzed Nucleophilic Fluorination Using Potassium Fluoride. Org. Lett. 2021, 23, 9640-9644.
22.Li, T.; Xu, B., Mechanically Strong Heterogeneous Catalysts via Immobilization of Powderous Catalysts to Porous Plastic Tablets. Chin. J. Chem . 2021, 39, 2673-2678.
23.Li, T.; Hammond, G. B.; Xu, B., Cobalt-Catalyzed Aerobic Oxidative Cleavage of Alkyl Aldehydes: Synthesis of Ketones, Esters, Amides, and α-Ketoamides. Chem. Eur. J. 2021, 27, 9737-9741.
24.Chen, G.; Xu, B., Mild Base-Promoted Tandem Nucleophilic Substitution/Decarboxylation/Hydroamination: Access to 3-Sulfonylindoles and 2-Methyleneindophenols. Org. Lett. 2021, 23, 9157-9162.
聯(lián)系電話： 6779-2188 E-MAIL：bo.xu@dhu.edu.cn
